INSR Break Apart FISH Probe
Empire Genomics’ INSR Break Apart FISH Probe is designed to flank the INSR gene and is typically used for detecting INSR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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INSRBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
INSRBA-20-AQOR | 20 (40 μL) | 200 μL | ||
INSRBA-20-GOGR | 20 (40 μL) | 200 μL | ||
INSRBA-20-GORE | 20 (40 μL) | 200 μL | ||
INSRBA-20-GRGO | 20 (40 μL) | 200 μL | ||
INSRBA-20-GRRE | 20 (40 μL) | 200 μL | ||
INSRBA-20-ORGR | 20 (40 μL) | 200 μL | ||
INSRBA-20-REGO | 20 (40 μL) | 200 μL | ||
INSRBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: INSR
Gene Name: Insulin Receptor
Chromosome: CHR19: 7112265-7294011
Locus: 19p13.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: INSR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: INSR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping