INSR FISH Probe
The INSR FISH probe is designed to hybridize to the INSR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| INSR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| INSR-20-RE | 20 (40 μL) | 200 μL |  |
|
| INSR-20-GO | 20 (40 μL) | 200 μL |  |
|
| INSR-20-GR | 20 (40 μL) | 200 μL |  |
|
| INSR-20-AQ | 20 (40 μL) | 200 μL |  |
|
| INSR-20-DIG | 20 (40 μL) | 200 μL |  |
|
| INSR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: INSR
Gene Name: Insulin Receptor
Chromosome: CHR19: 7112265-7294011
Locus: 19p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: INSR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: INSR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping