INSIG1 Break Apart FISH Probe
Empire Genomics’ INSIG1 Break Apart FISH Probe is designed to flank the INSIG1 gene and is typically used for detecting INSIG1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| INSIG1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-GORE | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-GROR | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-REGO | 20 (40 μL) | 200 μL |
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| INSIG1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism, lipogenesis, and glucose homeostasis. The encoded protein has six transmembrane helices which contain an effector protein binding site. It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), and is essential for the sterol-mediated trafficking of these two proteins. It promotes the endoplasmic reticulum retention of SCAP and the ubiquitin-mediated degradation of HMG-CoA reductase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Gene Details
Gene Symbol: INSIG1
Gene Name: Insulin Induced Gene 1
Chromosome: CHR7: 155089485-155101945
Locus: 7q36.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: INSIG1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: INSIG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping