INS Break Apart FISH Probe
Empire Genomics’ INS Break Apart FISH Probe is designed to flank the INS gene and is typically used for detecting INS rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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INSBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
INSBA-20-AQOR | 20 (40 μL) | 200 μL | ||
INSBA-20-GOGR | 20 (40 μL) | 200 μL | ||
INSBA-20-GORE | 20 (40 μL) | 200 μL | ||
INSBA-20-GRGO | 20 (40 μL) | 200 μL | ||
INSBA-20-GRRE | 20 (40 μL) | 200 μL | ||
INSBA-20-ORGR | 20 (40 μL) | 200 μL | ||
INSBA-20-REGO | 20 (40 μL) | 200 μL | ||
INSBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Details
Gene Symbol: INS
Gene Name: Insulin
Chromosome: CHR11: 2181008-2182439
Locus: 11p15.5
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: INS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: INS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping