IMPDH FISH Probe
The IMPDH FISH probe is designed to hybridize to the IMPDH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
IMPDH2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
IMPDH2-20-RE | 20 (40 μL) | 200 μL | ||
IMPDH2-20-GO | 20 (40 μL) | 200 μL | ||
IMPDH2-20-GR | 20 (40 μL) | 200 μL | ||
IMPDH2-20-AQ | 20 (40 μL) | 200 μL | ||
IMPDH2-20-DIG | 20 (40 μL) | 200 μL | ||
IMPDH2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IMPDH2
Gene Name: Inosine Monophosphate Dehydrogenase 2
Chromosome: CHR3: 49061761-49066875
Locus: 3p21.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IMPDH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IMPDH2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping