IMP-4 FISH Probe
The IMP-4 FISH probe is designed to hybridize to the IMP-4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPPL2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-RE | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-GO | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-GR | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPPL2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: SPPL2B
Gene Name: Signal Peptide Peptidase Like 2B
Chromosome: CHR19: 2328628-2355100
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: IMP-4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPPL2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping