ILT-4 FISH Probe
The ILT-4 FISH probe is designed to hybridize to the ILT-4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LILRB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-RE | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-GO | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-GR | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| LILRB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LILRB2
Gene Name: Leukocyte Immunoglobulin Like Receptor B2
Chromosome: CHR19: 54777674-54785033
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ILT-4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LILRB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping