IL7 FISH Probe
The IL7 FISH probe is designed to hybridize to the IL7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
IL7-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
IL7-20-RE | 20 (40 μL) | 200 μL | ||
IL7-20-GO | 20 (40 μL) | 200 μL | ||
IL7-20-GR | 20 (40 μL) | 200 μL | ||
IL7-20-AQ | 20 (40 μL) | 200 μL | ||
IL7-20-DIG | 20 (40 μL) | 200 μL | ||
IL7-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: IL7
Gene Name: Interleukin 7
Chromosome: CHR8: 79645006-79717758
Locus: 8q21.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping