IL6ST Break Apart FISH Probe
Empire Genomics’ IL6ST Break Apart FISH Probe is designed to flank the IL6ST gene and is typically used for detecting IL6ST rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL6STBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL6STBA-20-AQOR | 20 (40 μL) | 200 μL |
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| IL6STBA-20-GOGR | 20 (40 μL) | 200 μL |
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| IL6STBA-20-GORE | 20 (40 μL) | 200 μL |
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| IL6STBA-20-GRGO | 20 (40 μL) | 200 μL |
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| IL6STBA-20-GRRE | 20 (40 μL) | 200 μL |
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| IL6STBA-20-ORGR | 20 (40 μL) | 200 μL |
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| IL6STBA-20-REGO | 20 (40 μL) | 200 μL |
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| IL6STBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: IL6ST
Gene Name: Interleukin 6 Signal Transducer
Chromosome: CHR5: 55230924-55290821
Locus: 5q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL6ST FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL6ST-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping