IL2RB FISH Probe
The IL2RB FISH probe is designed to hybridize to the IL2RB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL2RB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-RE | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-GO | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-GR | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL2RB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. [provided by RefSeq, Sep 2016]
Gene Details
Gene Symbol: IL2RB
Gene Name: Interleukin 2 Receptor Subunit Beta
Chromosome: CHR22: 37521879-37545962
Locus: 22q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL2RB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL2RB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping