IL21R FISH Probe
The IL21R FISH probe is designed to hybridize to the IL21R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL21R-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL21R-20-RE | 20 (40 μL) | 200 μL |  |
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| IL21R-20-GO | 20 (40 μL) | 200 μL |  |
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| IL21R-20-GR | 20 (40 μL) | 200 μL |  |
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| IL21R-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL21R-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL21R-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: IL21R
Gene Name: Interleukin 21 Receptor
Chromosome: CHR16: 27413482-27463363
Locus: 16p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL21R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL21R-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping