IL1B FISH Probe
The IL1B FISH probe is designed to hybridize to the IL1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL1B-20-RE | 20 (40 μL) | 200 μL |  |
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| IL1B-20-GO | 20 (40 μL) | 200 μL |  |
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| IL1B-20-GR | 20 (40 μL) | 200 μL |  |
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| IL1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IL1B
Gene Name: Interleukin 1 Beta
Chromosome: CHR2: 113587336-113594356
Locus: 2q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping