IL15 Break Apart FISH Probe
Empire Genomics’ IL15 Break Apart FISH Probe is designed to flank the IL15 gene and is typically used for detecting IL15 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IL15BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IL15BA-20-AQOR | 20 (40 μL) | 200 μL |
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| IL15BA-20-GOGR | 20 (40 μL) | 200 μL |
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| IL15BA-20-GORE | 20 (40 μL) | 200 μL |
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| IL15BA-20-GRGO | 20 (40 μL) | 200 μL |
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| IL15BA-20-GROR | 20 (40 μL) | 200 μL |
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| IL15BA-20-GRRE | 20 (40 μL) | 200 μL |
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| IL15BA-20-REGO | 20 (40 μL) | 200 μL |
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| IL15BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: IL15
Gene Name: Interleukin 15
Chromosome: CHR4: 142557748-142655140
Locus: 4q31.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL15 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL15-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping