IL10X FISH Probe
The IL10X FISH probe is designed to hybridize to the IL10X gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL10-20-RE | 20 (40 μL) | 200 μL |  |
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| IL10-20-GO | 20 (40 μL) | 200 μL |  |
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| IL10-20-GR | 20 (40 μL) | 200 μL |  |
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| IL10-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL10-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Gene Details
Gene Symbol: IL10
Gene Name: Interleukin 10
Chromosome: CHR1: 206940947-206945839
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL10X FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping