IL-5RA FISH Probe
The IL-5RA FISH probe is designed to hybridize to the IL-5RA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL5RA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-RE | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-GO | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-GR | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL5RA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
Gene Details
Gene Symbol: IL5RA
Gene Name: Interleukin 5 Receptor Subunit Alpha
Chromosome: CHR3: 3108007-3152058
Locus: 3p26.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL-5RA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL5RA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping