IL-4-STAT FISH Probe
The IL-4-STAT FISH probe is designed to hybridize to the IL-4-STAT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| STAT6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| STAT6-20-RE | 20 (40 μL) | 200 μL |  |
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| STAT6-20-GO | 20 (40 μL) | 200 μL |  |
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| STAT6-20-GR | 20 (40 μL) | 200 μL |  |
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| STAT6-20-AQ | 20 (40 μL) | 200 μL |  |
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| STAT6-20-DIG | 20 (40 μL) | 200 μL |  |
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| STAT6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: STAT6
Gene Name: Signal Transducer And Activator Of Transcription 6
Chromosome: CHR12: 57489186-57505196
Locus: 12q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL-4-STAT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: STAT6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping