IL-24 FISH Probe
The IL-24 FISH probe is designed to hybridize to the IL-24 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL24-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| IL24-20-RE | 20 (40 μL) | 200 μL |  |
|
| IL24-20-GO | 20 (40 μL) | 200 μL |  |
|
| IL24-20-GR | 20 (40 μL) | 200 μL |  |
|
| IL24-20-AQ | 20 (40 μL) | 200 μL |  |
|
| IL24-20-DIG | 20 (40 μL) | 200 μL |  |
|
| IL24-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IL24
Gene Name: Interleukin 24
Chromosome: CHR1: 207070787-207077484
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: IL-24 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL24-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping