IL-18BP FISH Probe
The IL-18BP FISH probe is designed to hybridize to the IL-18BP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL18BP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-RE | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-GO | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-GR | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL18BP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: IL18BP
Gene Name: Interleukin 18 Binding Protein
Chromosome: CHR11: 71709957-71713850
Locus: 11q13.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL-18BP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL18BP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping