IL-13 FISH Probe
The IL-13 FISH probe is designed to hybridize to the IL-13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL13-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| IL13-20-RE | 20 (40 μL) | 200 μL |  |
|
| IL13-20-GO | 20 (40 μL) | 200 μL |  |
|
| IL13-20-GR | 20 (40 μL) | 200 μL |  |
|
| IL13-20-AQ | 20 (40 μL) | 200 μL |  |
|
| IL13-20-DIG | 20 (40 μL) | 200 μL |  |
|
| IL13-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IL13
Gene Name: Interleukin 13
Chromosome: CHR5: 131993864-131996801
Locus: 5q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: IL-13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL13-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping