IL-12RB2 FISH Probe
The IL-12RB2 FISH probe is designed to hybridize to the IL-12RB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IL12RB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-RE | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-GO | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-GR | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| IL12RB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Details
Gene Symbol: IL12RB2
Gene Name: Interleukin 12 Receptor Subunit Beta 2
Chromosome: CHR1: 67773046-67862583
Locus: 1p31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IL-12RB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IL12RB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping