IIAE2 FISH Probe
The IIAE2 FISH probe is designed to hybridize to the IIAE2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TLR3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TLR3-20-RE | 20 (40 μL) | 200 μL |  |
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| TLR3-20-GO | 20 (40 μL) | 200 μL |  |
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| TLR3-20-GR | 20 (40 μL) | 200 μL |  |
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| TLR3-20-AQ | 20 (40 μL) | 200 μL |  |
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| TLR3-20-DIG | 20 (40 μL) | 200 μL |  |
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| TLR3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: TLR3
Gene Name: Toll Like Receptor 3
Chromosome: CHR4: 186990308-187006252
Locus: 4q35.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IIAE2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TLR3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping