IGLV FISH Probe
The IGLV FISH probe is designed to hybridize to the IGLV gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGLL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-RE | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-GO | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-GR | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| IGLL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IGLL1
Gene Name: Immunoglobulin Lambda Like Polypeptide 1
Chromosome: CHR22: 23915312-23922495
Locus: 22q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IGLV FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IGLL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping