IGF2R FISH Probe
The IGF2R FISH probe is designed to hybridize to the IGF2R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGF2R-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-RE | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-GO | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-GR | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-AQ | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-DIG | 20 (40 μL) | 200 μL |  |
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| IGF2R-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: IGF2R
Gene Name: Insulin Like Growth Factor 2 Receptor
Chromosome: CHR6: 160390130-160527583
Locus: 6q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IGF2R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IGF2R-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping