IGF-IR FISH Probe
The IGF-IR FISH probe is designed to hybridize to the IGF-IR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IGF1R-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-RE | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-GO | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-GR | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-AQ | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-DIG | 20 (40 μL) | 200 μL |  |
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| IGF1R-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: IGF1R
Gene Name: Insulin Like Growth Factor 1 Receptor
Chromosome: CHR15: 99192760-99507759
Locus: 15q26.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IGF-IR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IGF1R-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping