IDO1 FISH Probe
The IDO1 FISH probe is designed to hybridize to the IDO1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IDO1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IDO1-20-RE | 20 (40 μL) | 200 μL |  |
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| IDO1-20-GO | 20 (40 μL) | 200 μL |  |
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| IDO1-20-GR | 20 (40 μL) | 200 μL |  |
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| IDO1-20-AQ | 20 (40 μL) | 200 μL |  |
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| IDO1-20-DIG | 20 (40 μL) | 200 μL |  |
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| IDO1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: IDO1
Gene Name: Indoleamine 2,3-dioxygenase 1
Chromosome: CHR8: 39771327-39786309
Locus: 8p11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IDO1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IDO1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping