IDH3B FISH Probe
The IDH3B FISH probe is designed to hybridize to the IDH3B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IDH3B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-RE | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-GO | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-GR | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-AQ | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-DIG | 20 (40 μL) | 200 μL |  |
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| IDH3B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2016]
Gene Details
Gene Symbol: IDH3B
Gene Name: Isocitrate Dehydrogenase 3 (NAD(+)) Beta
Chromosome: CHR20: 2639040-2644843
Locus: 20p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IDH3B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IDH3B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping