IDH2 Break Apart FISH Probe
Empire Genomics’ IDH2 Break Apart FISH Probe is designed to flank the IDH2 gene and is typically used for detecting IDH2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IDH2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| IDH2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| IDH2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| IDH2BA-20-GORE | 20 (40 μL) | 200 μL |
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| IDH2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| IDH2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| IDH2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| IDH2BA-20-REGO | 20 (40 μL) | 200 μL |
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| IDH2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: IDH2
Gene Name: Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial
Chromosome: CHR15: 90627211-90645708
Locus: 15q26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IDH2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IDH2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping