ICH-3 FISH Probe
The ICH-3 FISH probe is designed to hybridize to the ICH-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CASP5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CASP5-20-RE | 20 (40 μL) | 200 μL |  |
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| CASP5-20-GO | 20 (40 μL) | 200 μL |  |
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| CASP5-20-GR | 20 (40 μL) | 200 μL |  |
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| CASP5-20-AQ | 20 (40 μL) | 200 μL |  |
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| CASP5-20-DIG | 20 (40 μL) | 200 μL |  |
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| CASP5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: CASP5
Gene Name: Caspase 5
Chromosome: CHR11: 104864966-104893895
Locus: 11q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ICH-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CASP5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping