ICD-M FISH Probe
The ICD-M FISH probe is designed to hybridize to the ICD-M gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IDH2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IDH2-20-RE | 20 (40 μL) | 200 μL |  |
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| IDH2-20-GO | 20 (40 μL) | 200 μL |  |
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| IDH2-20-GR | 20 (40 μL) | 200 μL |  |
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| IDH2-20-AQ | 20 (40 μL) | 200 μL |  |
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| IDH2-20-DIG | 20 (40 μL) | 200 μL |  |
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| IDH2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Details
Gene Symbol: IDH2
Gene Name: Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial
Chromosome: CHR15: 90627211-90645708
Locus: 15q26.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ICD-M FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IDH2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping