IBTK Break Apart FISH Probe
Empire Genomics’ IBTK Break Apart FISH Probe is designed to flank the IBTK gene and is typically used for detecting IBTK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IBTKBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| IBTKBA-20-AQOR | 20 (40 μL) | 200 μL |
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| IBTKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| IBTKBA-20-GORE | 20 (40 μL) | 200 μL |
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| IBTKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| IBTKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| IBTKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| IBTKBA-20-REGO | 20 (40 μL) | 200 μL |
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| IBTKBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: IBTK
Gene Name: Inhibitor Of Bruton Tyrosine Kinase
Chromosome: CHR6: 82879955-82957448
Locus: 6q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IBTK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IBTK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping