I2PP2A FISH Probe
The I2PP2A FISH probe is designed to hybridize to the I2PP2A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SET-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SET-20-RE | 20 (40 μL) | 200 μL |  |
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| SET-20-GO | 20 (40 μL) | 200 μL |  |
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| SET-20-GR | 20 (40 μL) | 200 μL |  |
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| SET-20-AQ | 20 (40 μL) | 200 μL |  |
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| SET-20-DIG | 20 (40 μL) | 200 μL |  |
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| SET-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Details
Gene Symbol: SET
Gene Name: SET Nuclear Proto-oncogene
Chromosome: CHR9: 131445933-131458675
Locus: 9q34.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: I2PP2A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SET-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping