HYPDH FISH Probe
The HYPDH FISH probe is designed to hybridize to the HYPDH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRODH2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PRODH2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene catalyzes the first step in the catabolism of trans-4-hydroxy-L-proline, an amino acid derivative obtained through food intake and collagen turnover. One of the downstream products of this catabolism is glyoxylate, which in people with disorders of glyoxalate metabolism can lead to an increase in oxalate levels and the formation of calcium-oxalate kidney stones. Therefore, this gene may serve as a therapeutic target against primary hyperoxalurias (PH). This gene is similar to proline dehydrogenase (oxidase) 1, a mitochondrial enzyme that catalyzes the first step in proline catabolism. [provided by RefSeq, Jan 2017]
Gene Details
Gene Symbol: PRODH2
Gene Name: Proline Dehydrogenase 2
Chromosome: CHR19: 36290891-36304201
Locus: 19q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HYPDH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PRODH2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping