HYAL2 FISH Probe
The HYAL2 FISH probe is designed to hybridize to the HYAL2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
HYAL2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
HYAL2-20-RE | 20 (40 μL) | 200 μL | ||
HYAL2-20-GO | 20 (40 μL) | 200 μL | ||
HYAL2-20-GR | 20 (40 μL) | 200 μL | ||
HYAL2-20-AQ | 20 (40 μL) | 200 μL | ||
HYAL2-20-DIG | 20 (40 μL) | 200 μL | ||
HYAL2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: HYAL2
Gene Name: Hyaluronoglucosaminidase 2
Chromosome: CHR3: 50355220-50360281
Locus: 3p21.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HYAL2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HYAL2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping