HUWE1 FISH Probe
The HUWE1 FISH probe is designed to hybridize to the HUWE1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HUWE1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-RE | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-GO | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-GR | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| HUWE1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic cognitive disability. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: HUWE1
Gene Name: HECT, UBA And WWE Domain Containing 1, E3 Ubiquitin Protein Ligase
Chromosome: CHRX: 53559062-53713673
Locus: Xp11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: HUWE1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HUWE1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping