HUS1 FISH Probe
The HUS1 FISH probe is designed to hybridize to the HUS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HUS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HUS1-20-RE | 20 (40 μL) | 200 μL |  |
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| HUS1-20-GO | 20 (40 μL) | 200 μL |  |
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| HUS1-20-GR | 20 (40 μL) | 200 μL |  |
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| HUS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| HUS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| HUS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: HUS1
Gene Name: HUS1 Checkpoint Clamp Component
Chromosome: CHR7: 48002884-48019222
Locus: 7p12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HUS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HUS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping