HUG-BR1 FISH Probe
The HUG-BR1 FISH probe is designed to hybridize to the HUG-BR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UGT1A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-RE | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-GO | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-GR | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-AQ | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-DIG | 20 (40 μL) | 200 μL |  |
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| UGT1A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UGT1A1
Gene Name: UDP Glucuronosyltransferase Family 1 Member A1
Chromosome: CHR2: 234668918-234681945
Locus: 2q37.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HUG-BR1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UGT1A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping