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HSD11B1 FISH Probe

The HSD11B1 FISH probe is designed to hybridize to the HSD11B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
HSD11B1-20-OR  (Standard Design) 20 (40 μL) 200 μL
HSD11B1-20-RE 20 (40 μL) 200 μL
HSD11B1-20-GO 20 (40 μL) 200 μL
HSD11B1-20-GR 20 (40 μL) 200 μL
HSD11B1-20-AQ 20 (40 μL) 200 μL
HSD11B1-20-DIG 20 (40 μL) 200 μL
HSD11B1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]

Gene Details

Gene Symbol: HSD11B1

Gene Name: Hydroxysteroid 11-beta Dehydrogenase 1

Chromosome: CHR1: 209859524-209908295

Locus: 1q32.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: HSD11B1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: HSD11B1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping