HSD11B1 FISH Probe
The HSD11B1 FISH probe is designed to hybridize to the HSD11B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HSD11B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-RE | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-GO | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-GR | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| HSD11B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
Gene Details
Gene Symbol: HSD11B1
Gene Name: Hydroxysteroid 11-beta Dehydrogenase 1
Chromosome: CHR1: 209859524-209908295
Locus: 1q32.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HSD11B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HSD11B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping