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HSCB FISH Probe

The HSCB FISH probe is designed to hybridize to the HSCB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
HSCB-20-OR  (Standard Design) 20 (40 μL) 200 μL
HSCB-20-RE 20 (40 μL) 200 μL
HSCB-20-GO 20 (40 μL) 200 μL
HSCB-20-GR 20 (40 μL) 200 μL
HSCB-20-AQ 20 (40 μL) 200 μL
HSCB-20-DIG 20 (40 μL) 200 μL
HSCB-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Gene Details

Gene Symbol: HSCB

Gene Name: HscB Mitochondrial Iron-sulfur Cluster Cochaperone

Chromosome: CHR22: 29138042-29153496

Locus: 22q12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: HSCB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: HSCB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping