HRAS FISH Probe
The HRAS FISH probe is designed to hybridize to the HRAS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HRAS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HRAS-20-RE | 20 (40 μL) | 200 μL |  |
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| HRAS-20-GO | 20 (40 μL) | 200 μL |  |
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| HRAS-20-GR | 20 (40 μL) | 200 μL |  |
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| HRAS-20-AQ | 20 (40 μL) | 200 μL |  |
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| HRAS-20-DIG | 20 (40 μL) | 200 μL |  |
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| HRAS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, cognitive disability, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HRAS
Gene Name: HRas Proto-oncogene, GTPase
Chromosome: CHR11: 532241-535550
Locus: 11p15.5
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HRAS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HRAS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping