HPCN1 FISH Probe
The HPCN1 FISH probe is designed to hybridize to the HPCN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNA5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNA5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: KCNA5
Gene Name: Potassium Voltage-gated Channel Subfamily A Member 5
Chromosome: CHR12: 5153084-5155949
Locus: 12p13.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HPCN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNA5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping