HNPCC7 FISH Probe
The HNPCC7 FISH probe is designed to hybridize to the HNPCC7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MLH3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MLH3-20-RE | 20 (40 μL) | 200 μL |  |
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| MLH3-20-GO | 20 (40 μL) | 200 μL |  |
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| MLH3-20-GR | 20 (40 μL) | 200 μL |  |
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| MLH3-20-AQ | 20 (40 μL) | 200 μL |  |
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| MLH3-20-DIG | 20 (40 μL) | 200 μL |  |
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| MLH3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MLH3
Gene Name: MutL Homolog 3
Chromosome: CHR14: 75480466-75518235
Locus: 14q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HNPCC7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MLH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping