HNPCC3 FISH Probe
The HNPCC3 FISH probe is designed to hybridize to the HNPCC3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PMS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PMS1-20-RE | 20 (40 μL) | 200 μL |  |
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| PMS1-20-GO | 20 (40 μL) | 200 μL |  |
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| PMS1-20-GR | 20 (40 μL) | 200 μL |  |
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| PMS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PMS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PMS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PMS1
Gene Name: PMS1 Homolog 1, Mismatch Repair System Component
Chromosome: CHR2: 190648810-190742355
Locus: 2q32.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HNPCC3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PMS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping