HML FISH Probe
The HML FISH probe is designed to hybridize to the HML gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ISCU-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ISCU-20-RE | 20 (40 μL) | 200 μL |  |
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| ISCU-20-GO | 20 (40 μL) | 200 μL |  |
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| ISCU-20-GR | 20 (40 μL) | 200 μL |  |
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| ISCU-20-AQ | 20 (40 μL) | 200 μL |  |
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| ISCU-20-DIG | 20 (40 μL) | 200 μL |  |
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| ISCU-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: ISCU
Gene Name: Iron-sulfur Cluster Assembly Enzyme
Chromosome: CHR12: 108956293-108963160
Locus: 12q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HML FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ISCU-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping