HME FISH Probe
The HME FISH probe is designed to hybridize to the HME gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MMP12-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MMP12-20-RE | 20 (40 μL) | 200 μL |  |
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| MMP12-20-GO | 20 (40 μL) | 200 μL |  |
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| MMP12-20-GR | 20 (40 μL) | 200 μL |  |
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| MMP12-20-AQ | 20 (40 μL) | 200 μL |  |
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| MMP12-20-DIG | 20 (40 μL) | 200 μL |  |
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| MMP12-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: MMP12
Gene Name: Matrix Metallopeptidase 12
Chromosome: CHR11: 102733463-102745764
Locus: 11q22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HME FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MMP12-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping