HLA-F Break Apart FISH Probe
Empire Genomics’ HLA-F Break Apart FISH Probe is designed to flank the HLA-F gene and is typically used for detecting HLA-F rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HLA-FBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-AQOR | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-GOGR | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-GORE | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-GRGO | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-GROR | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-GRRE | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-REGO | 20 (40 μL) | 200 μL |
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| HLA-FBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HLA-F
Gene Name: Major Histocompatibility Complex, Class I, F
Chromosome: CHR6_mcf_hap5: 991650-1359214
Locus: 6p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HLA-F FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HLA-F-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping