HLA-DRA FISH Probe
The HLA-DRA FISH probe is designed to hybridize to the HLA-DRA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HLA-DRA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-RE | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-GO | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-GR | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-AQ | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-DIG | 20 (40 μL) | 200 μL |  |
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| HLA-DRA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HLA-DRA
Gene Name: Major Histocompatibility Complex, Class II, DR Alpha
Chromosome: CHR6_mann_hap4: 3749678-3754894
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HLA-DRA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HLA-DRA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping