HLA-DQB2 Break Apart FISH Probe
Empire Genomics’ HLA-DQB2 Break Apart FISH Probe is designed to flank the HLA-DQB2 gene and is typically used for detecting HLA-DQB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| HLA-DQB2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-GORE | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-REGO | 20 (40 μL) | 200 μL |
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| HLA-DQB2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
HLA-DQB2 belongs to the family of HLA class II beta chain paralogs. Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. They play a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). Polymorphisms in the alpha and beta chains specify the peptide binding specificity, and typing for these polymorphisms is routinely done for bone marrow transplantation. However this gene, HLA-DQB2, is not routinely typed, as it is not thought to have an effect on transplantation. There is conflicting evidence in the literature and public sequence databases for the protein-coding capacity of HLA-DQB2. Because there is evidence of transcription and an intact ORF, HLA-DQB2 is represented in Entrez Gene and in RefSeq as a protein-coding locus. [provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: HLA-DQB2
Gene Name: Major Histocompatibility Complex, Class II, DQ Beta 2
Chromosome: CHR6_qbl_hap6: 3955994-3963453
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HLA-DQB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HLA-DQB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping