HIRA FISH Probe
The HIRA FISH probe is designed to hybridize to the HIRA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HIRA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HIRA-20-RE | 20 (40 μL) | 200 μL |  |
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| HIRA-20-GO | 20 (40 μL) | 200 μL |  |
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| HIRA-20-GR | 20 (40 μL) | 200 μL |  |
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| HIRA-20-AQ | 20 (40 μL) | 200 μL |  |
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| HIRA-20-DIG | 20 (40 μL) | 200 μL |  |
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| HIRA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: HIRA
Gene Name: Histone Cell Cycle Regulator
Chromosome: CHR22: 19318223-19419219
Locus: 22q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HIRA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HIRA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping