HIF1A FISH Probe
The HIF1A FISH probe is designed to hybridize to the HIF1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| HIF1A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-RE | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-GO | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-GR | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-AQ | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-DIG | 20 (40 μL) | 200 μL |  |
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| HIF1A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
Gene Details
Gene Symbol: HIF1A
Gene Name: Hypoxia Inducible Factor 1 Alpha Subunit
Chromosome: CHR14: 62162118-62214977
Locus: 14q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HIF1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: HIF1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping