HH13 FISH Probe
The HH13 FISH probe is designed to hybridize to the HH13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KISS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KISS1-20-RE | 20 (40 μL) | 200 μL |  |
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| KISS1-20-GO | 20 (40 μL) | 200 μL |  |
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| KISS1-20-GR | 20 (40 μL) | 200 μL |  |
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| KISS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| KISS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| KISS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: KISS1
Gene Name: KiSS-1 Metastasis-suppressor
Chromosome: CHR1: 204159468-204165619
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: HH13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KISS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping